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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2003-11-10
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pubmed:abstractText |
Heparin-induced thrombocytopenia (HIT) is a well-known complication of heparin exposure and presents a clinical dilemma for patients undergoing percutaneous intervention (PI). Heparin cannot be used for thrombin inhibition and direct thrombin inhibitors offer an attractive alternative to heparin. We report our experience with lepirudin, a recombinant hirudin, used for PI in HIT patients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants,
http://linkedlifedata.com/resource/pubmed/chemical/Heparin,
http://linkedlifedata.com/resource/pubmed/chemical/Hirudins,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin Fab Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Glycoprotein GPIIb-IIIa...,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tyrosine,
http://linkedlifedata.com/resource/pubmed/chemical/abciximab,
http://linkedlifedata.com/resource/pubmed/chemical/eptifibatide,
http://linkedlifedata.com/resource/pubmed/chemical/lepirudin,
http://linkedlifedata.com/resource/pubmed/chemical/tirofiban
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1042-3931
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
617-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14608129-Angioplasty, Balloon,
pubmed-meshheading:14608129-Antibodies, Monoclonal,
pubmed-meshheading:14608129-Anticoagulants,
pubmed-meshheading:14608129-Drug Therapy, Combination,
pubmed-meshheading:14608129-Female,
pubmed-meshheading:14608129-Heparin,
pubmed-meshheading:14608129-Hirudins,
pubmed-meshheading:14608129-Humans,
pubmed-meshheading:14608129-Immunoglobulin Fab Fragments,
pubmed-meshheading:14608129-Male,
pubmed-meshheading:14608129-Peptides,
pubmed-meshheading:14608129-Platelet Aggregation Inhibitors,
pubmed-meshheading:14608129-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:14608129-Prospective Studies,
pubmed-meshheading:14608129-Recombinant Proteins,
pubmed-meshheading:14608129-Thrombocytopenia,
pubmed-meshheading:14608129-Treatment Outcome,
pubmed-meshheading:14608129-Tyrosine
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pubmed:year |
2003
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pubmed:articleTitle |
Use of lepirudin during percutaneous vascular interventions in patients with heparin-induced thrombocytopenia.
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pubmed:affiliation |
Loyola University Medical Center, Maywood, IL, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
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