rdf:type |
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lifeskim:mentions |
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pubmed:issue |
17
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pubmed:dateCreated |
2003-11-5
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pubmed:abstractText |
Although low levels of high-density lipoprotein cholesterol (HDL-C) increase risk for coronary disease, no data exist regarding potential benefits of administration of HDL-C or an HDL mimetic. ApoA-I Milano is a variant of apolipoprotein A-I identified in individuals in rural Italy who exhibit very low levels of HDL. Infusion of recombinant ApoA-I Milano-phospholipid complexes produces rapid regression of atherosclerosis in animal models.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1538-3598
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pubmed:author |
pubmed-author:BlankenshipJames CJC,
pubmed-author:CooperChristopher JCJ,
pubmed-author:CroweTimT,
pubmed-author:EatonGregory MGM,
pubmed-author:GrinesCindy LCL,
pubmed-author:HalpernStephenS,
pubmed-author:KerenskyRichardR,
pubmed-author:LauerMichael AMA,
pubmed-author:NissenSteven ESE,
pubmed-author:SchoenhagenPaulP,
pubmed-author:SheldonW ScottWS,
pubmed-author:TsunodaTaroT,
pubmed-author:TuzcuE MuratEM,
pubmed-author:YasinMuhammadM
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pubmed:issnType |
Electronic
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pubmed:day |
5
|
pubmed:volume |
290
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
2292-300
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14600188-Adult,
pubmed-meshheading:14600188-Aged,
pubmed-meshheading:14600188-Aged, 80 and over,
pubmed-meshheading:14600188-Angina, Unstable,
pubmed-meshheading:14600188-Apolipoprotein A-I,
pubmed-meshheading:14600188-Coronary Angiography,
pubmed-meshheading:14600188-Coronary Artery Disease,
pubmed-meshheading:14600188-Double-Blind Method,
pubmed-meshheading:14600188-Female,
pubmed-meshheading:14600188-Humans,
pubmed-meshheading:14600188-Male,
pubmed-meshheading:14600188-Middle Aged,
pubmed-meshheading:14600188-Myocardial Infarction,
pubmed-meshheading:14600188-Phosphatidylcholines,
pubmed-meshheading:14600188-Prospective Studies,
pubmed-meshheading:14600188-Ultrasonography, Interventional
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pubmed:year |
2003
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pubmed:articleTitle |
Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial.
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pubmed:affiliation |
Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. nissens@ccf.org
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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