The presence of nitric oxide (NO) in high concentrations has been described in the nasal mucosa of patients with untreated allergic rhinitis. We sought to examine the role of exogenous, as well as endogenous, NO in the production of collagen type I and type III by human nasal fibroblasts.
Department of Otolaryngology, Sir Mortimer B. Davis Jewish General Hospital, and Meakins-Christie Laboratories, Respiratory Division, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.
