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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-11-4
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pubmed:abstractText |
Cirrhosis and portal hypertension due to chronic common bile duct ligation reproduce the features of human hepatopulmonary syndrome, whereas portal hypertension alone due to partial portal vein ligation does not. Nitric oxide contributes to experimental hepatopulmonary syndrome, but the nitric oxide synthase forms involved remain controversial. Recently, increased pulmonary heme oxygenase-1 expression and carbon monoxide production have also been found after common bile duct ligation. Our aim was to explore the role of the heme oxygenase-1/carbon monoxide pathway in the pathogenesis of experimental hepatopulmonary syndrome.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Heme Oxygenase (Decyclizing),
http://linkedlifedata.com/resource/pubmed/chemical/Heme Oxygenase-1,
http://linkedlifedata.com/resource/pubmed/chemical/Metalloporphyrins,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Nos2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Nos3 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Protoporphyrins,
http://linkedlifedata.com/resource/pubmed/chemical/tin protoporphyrin IX
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1441-51
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14598260-Animals,
pubmed-meshheading:14598260-Common Bile Duct,
pubmed-meshheading:14598260-Enzyme Inhibitors,
pubmed-meshheading:14598260-Heme Oxygenase (Decyclizing),
pubmed-meshheading:14598260-Heme Oxygenase-1,
pubmed-meshheading:14598260-Hemodynamics,
pubmed-meshheading:14598260-Hepatopulmonary Syndrome,
pubmed-meshheading:14598260-Ligation,
pubmed-meshheading:14598260-Liver,
pubmed-meshheading:14598260-Lung,
pubmed-meshheading:14598260-Male,
pubmed-meshheading:14598260-Metalloporphyrins,
pubmed-meshheading:14598260-Nitric Oxide Synthase,
pubmed-meshheading:14598260-Nitric Oxide Synthase Type II,
pubmed-meshheading:14598260-Nitric Oxide Synthase Type III,
pubmed-meshheading:14598260-Portal System,
pubmed-meshheading:14598260-Protoporphyrins,
pubmed-meshheading:14598260-Rats,
pubmed-meshheading:14598260-Rats, Sprague-Dawley,
pubmed-meshheading:14598260-Tissue Distribution
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pubmed:year |
2003
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pubmed:articleTitle |
Analysis of pulmonary heme oxygenase-1 and nitric oxide synthase alterations in experimental hepatopulmonary syndrome.
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pubmed:affiliation |
Department of Internal Medicine, Liver Center, University of Alabama at Birmingham, 1918 University Boulevard, Birmingham, AL 35294-0005, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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