Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2003-11-4
pubmed:abstractText
Human endothelin-converting enzyme (ECE)-1, the key enzyme in endothelin biosynthesis, shows broad cell and tissue expression within the cardiovascular system. Expression of ECE-1c, which represents the major ECE-1 isoform, is directed by an alternative promoter, but the mechanisms of ECE-1c promoter regulation are largely unknown. As ECE-1c transcription is initiated from several start sites, we hypothesized that the ECE-1c promoter functions as a housekeeping promoter.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Aspartic Acid Endopeptidases, http://linkedlifedata.com/resource/pubmed/chemical/CCAAT-Binding Factor, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/E2F2 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/GATA2 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/GATA2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Metalloendopeptidases, http://linkedlifedata.com/resource/pubmed/chemical/NFYB protein, human, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Sp1 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/endothelin-converting enzyme
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0263-6352
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2111-24
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:14597855-Aspartic Acid Endopeptidases, pubmed-meshheading:14597855-CCAAT-Binding Factor, pubmed-meshheading:14597855-Cell Line, pubmed-meshheading:14597855-Consensus Sequence, pubmed-meshheading:14597855-DNA Methylation, pubmed-meshheading:14597855-DNA-Binding Proteins, pubmed-meshheading:14597855-Dinucleotide Repeats, pubmed-meshheading:14597855-E2F2 Transcription Factor, pubmed-meshheading:14597855-GATA2 Transcription Factor, pubmed-meshheading:14597855-Gene Expression Regulation, pubmed-meshheading:14597855-Genome, pubmed-meshheading:14597855-Humans, pubmed-meshheading:14597855-Metalloendopeptidases, pubmed-meshheading:14597855-Microsatellite Repeats, pubmed-meshheading:14597855-Polymorphism, Genetic, pubmed-meshheading:14597855-Promoter Regions, Genetic, pubmed-meshheading:14597855-RNA, Messenger, pubmed-meshheading:14597855-Repetitive Sequences, Nucleic Acid, pubmed-meshheading:14597855-Sp1 Transcription Factor, pubmed-meshheading:14597855-Transcription Factors, pubmed-meshheading:14597855-Transcriptional Activation
pubmed:year
2003
pubmed:articleTitle
Regulation of the major isoform of human endothelin-converting enzyme-1 by a strong housekeeping promoter modulated by polymorphic microsatellites.
pubmed:affiliation
Institute of Clinical Pharmacology and Toxicology, Charité - Campus Benjamin Franklin, Berlin, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't