Linked Life Data

14593725

Source:http://linkedlifedata.com/resource/pubmed/id/14593725

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-11-3
pubmed:abstractText
The nucleolus is the ribosome factory and also a multifunctional domain that plays an important role in nuclear organization and function. Interestingly, ribosome biogenesis appears directly related to cell growth and proliferation. The nucleolus corresponds to a very dynamic nuclear domain resulting from an equilibrium between the level of ribosomal RNA synthesis and the efficiency of ribosomal RNA processing. Ribosome biogenesis is regulated throughout interphase and stops during mitosis. The mitotic silencing of transcription, the distribution of the processing machinery, as well as the link between transcription and processing were found to be dependent on cyclin-dependent kinase(s).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1087-2957
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
301-8
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Regulators of nucleolar functions.
pubmed:affiliation
Institut Jacques Monod, 2 place Jussieu, 75251 Paris, France.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't