Source:http://linkedlifedata.com/resource/pubmed/id/14593244
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-10-31
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pubmed:abstractText |
Necrotizing enterocolitis (NEC) is an important neonatal disease with a high mortality rate; erythropoietin (Epo) is a hematopoietic growth factor. Functional Epo receptors are in the fetal and postnatal small bowel and their ligands are available for binding. Excessive nitric oxide (NO) production by an isoform of NO synthase inducible by inflammatory stimuli leads to changes in vascular permeability and tissue injury. The aim of this study was to investigate NO formation in an experimental model of NEC and the possible role of NO in the protection Epo provides against NEC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0006-3126
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2003 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
325-9
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:14593244-Animals,
pubmed-meshheading:14593244-Anoxia,
pubmed-meshheading:14593244-Enterocolitis, Necrotizing,
pubmed-meshheading:14593244-Erythropoietin,
pubmed-meshheading:14593244-Humans,
pubmed-meshheading:14593244-Intestinal Mucosa,
pubmed-meshheading:14593244-Intestines,
pubmed-meshheading:14593244-Nitrites,
pubmed-meshheading:14593244-Rats,
pubmed-meshheading:14593244-Rats, Wistar,
pubmed-meshheading:14593244-Recombinant Proteins
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pubmed:year |
2003
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pubmed:articleTitle |
Erythropoietin protects against necrotizing enterocolitis of newborn rats by the inhibiting nitric oxide formation.
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pubmed:affiliation |
Department of Pediatrics, School of Medicine, Dokuz Eylul University, Izmir, Turkey.
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pubmed:publicationType |
Journal Article
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