Linked Life Data

14592237

Source:http://linkedlifedata.com/resource/pubmed/id/14592237

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-10-31
pubmed:abstractText
We assessed the effectiveness and safety of melatonin in normalizing sleep in a 7-year-old blind child with a longstanding sleep/wake cycle disorder, using a double-masked, randomized treatment trial of placebo, a physiological dose (0.14 mg) and a supraphysiological dose (2.2 mg) of melatonin. Sleep onset and sleep offset were erratic and inappropriately early with placebo and low dose melatonin, but improved significantly on high dose melatonin. This report confirms that melatonin may be effective in treatment of disordered sleep rhythm in blind children, and illustrates a protocol that enables dose adjustment for optimal treatment response.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Mar
pubmed:issn
1389-9457
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
159-61
pubmed:dateRevised
2006-9-18
pubmed:year
2002
pubmed:articleTitle
Dose response to melatonin treatment for disordered sleep rhythm in a blind child.
pubmed:affiliation
Department of Pediatrics, University of Cincinnati College of Medicine and Children's Hospital Medical Center, Cincinnati, OH 45299-3039, USA. anita.cavallho@chmcc.org
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial