Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-10-31
pubmed:abstractText
Kaufman's critique of the literature on the associations between lead exposure and child intelligence raises important methodological and inferential points. We address the concerns he raises regarding measuring known and unknown confounders, statistical modeling, reverse causality and quality control. Mismeasurement of potential confounders of the lead-IQ relationship, such as parenting skills, parental intelligence, maternal smoking during pregnancy, or otitis media can either strengthen or weaken the estimated association between exposure and child intelligence. Despite some variability in design and measurement, a series of comprehensive prospective investigations in varied populations, by different sets of investigators, provided consistent replication; taken together these studies point to the conclusion that lead exposure has adverse consequences for child development, and that the deficits are likely to be small in comparison to the contribution of measured social factors.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
May
pubmed:issn
0887-6177
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-52
pubmed:year
2001
pubmed:articleTitle
Methodology, inference and causation: environmental lead exposure and childhood intelligence.
pubmed:affiliation
Columbia University, New York, NY, USA.
pubmed:publicationType
Journal Article, Comment