rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
11
|
pubmed:dateCreated |
2003-10-30
|
pubmed:abstractText |
Hearts from non-heart-beating organ donors are not transplanted because of risk of ischemia-reperfusion injury. We tested whether pharmacologic pre-conditioning with adenosine and the Na(+)/H(+) exchanger inhibitor, cariporide, combined with controlled reperfusion, would prevent injury in porcine hearts that had sustained 30 minutes of hypoxia/ischemia in closed-chest animals.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1053-2498
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1234-44
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:14585385-Adenosine,
pubmed-meshheading:14585385-Animals,
pubmed-meshheading:14585385-Anoxia,
pubmed-meshheading:14585385-Anti-Arrhythmia Agents,
pubmed-meshheading:14585385-Creatine Kinase,
pubmed-meshheading:14585385-Guanidines,
pubmed-meshheading:14585385-Heart,
pubmed-meshheading:14585385-Ischemic Preconditioning, Myocardial,
pubmed-meshheading:14585385-Myocardial Reperfusion Injury,
pubmed-meshheading:14585385-Myocardium,
pubmed-meshheading:14585385-Sulfones,
pubmed-meshheading:14585385-Swine,
pubmed-meshheading:14585385-Vasodilator Agents
|
pubmed:year |
2003
|
pubmed:articleTitle |
Pharmacologic pre-conditioning and controlled reperfusion prevent ischemia-reperfusion injury after 30 minutes of hypoxia/ischemia in porcine hearts.
|
pubmed:affiliation |
Department of Surgery, Temple University Health Sciences Center, Philadelphia, Pennsylvania 19140, USA.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|