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rdf:type |
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lifeskim:mentions |
umls-concept:C0026882,
umls-concept:C0043210,
umls-concept:C0178443,
umls-concept:C0206243,
umls-concept:C0241889,
umls-concept:C0376571,
umls-concept:C0598034,
umls-concept:C0926407,
umls-concept:C1519021,
umls-concept:C1704788,
umls-concept:C1708728
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pubmed:issue |
6
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pubmed:dateCreated |
2003-10-28
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pubmed:abstractText |
Ancestral mutations in BRCA1 and BRCA2 are common in people of Ashkenazi Jewish descent and are associated with a substantially increased risk of breast and ovarian cancer. Women considering mutation testing usually have several personal and family cancer characteristics, so predicting mutation status from one factor alone could be misleading. The aim of this study was to develop a simple algorithm to estimate the probability that an Ashkenazi Jewish woman carries an ancestral mutation, based on multiple predictive factors.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10090881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10213514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10353781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10359546,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10408690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10413426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10464625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10577931,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10577933,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10739756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-10854492,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-11133358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-11304778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-11857015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-8531968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-9042909,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-9145676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-9145677,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-9150153,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-9333265,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-9443863,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14580256-9634504
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1465-542X
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pubmed:author |
pubmed-author:AndrewsLesleyL,
pubmed-author:ApicellaCarmelC,
pubmed-author:BankierAgnesA,
pubmed-author:FisherSheila ASA,
pubmed-author:FriedlanderMichaelM,
pubmed-author:HodgsonShirley VSV,
pubmed-author:HopperJohn LJL,
pubmed-author:LewisCathryn MCM,
pubmed-author:SolomonEllenE,
pubmed-author:SoutheyMelissa CMC,
pubmed-author:TuckerKatherineK,
pubmed-author:VenterDeon JDJ
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
R206-16
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:14580256-Australia,
pubmed-meshheading:14580256-BRCA1 Protein,
pubmed-meshheading:14580256-BRCA2 Protein,
pubmed-meshheading:14580256-Breast Neoplasms,
pubmed-meshheading:14580256-Family Health,
pubmed-meshheading:14580256-Female,
pubmed-meshheading:14580256-Great Britain,
pubmed-meshheading:14580256-Heterozygote,
pubmed-meshheading:14580256-Humans,
pubmed-meshheading:14580256-Jews,
pubmed-meshheading:14580256-Logistic Models,
pubmed-meshheading:14580256-Male,
pubmed-meshheading:14580256-Mutation,
pubmed-meshheading:14580256-Ovarian Neoplasms
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pubmed:year |
2003
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pubmed:articleTitle |
Log odds of carrying an Ancestral Mutation in BRCA1 or BRCA2 for a Defined personal and family history in an Ashkenazi Jewish woman (LAMBDA).
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pubmed:affiliation |
Centre for Genetic Epidemiology, The University of Melbourne, Carlton, Victoria, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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