Linked Life Data

1457744

Source:http://linkedlifedata.com/resource/pubmed/id/1457744

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1993-1-13
pubmed:abstractText
Since melatonin causes considerable reduction in the thymic weight of chickens, the aim of the present study was to find out whether the bursa of Fabricius and the immune response are also affected by this substance. The results show that melatonin also acts on the bursa of Fabricius depending upon the administration route. When injected subcutaneously it does not reduce bursal weight and the histological pattern does not change, while primary and secondary immune responses are significantly lowered. When melatonin is introduced into the bursa, it causes a considerable decrease in bursal weight and the histological pattern is greatly modified. A significant reduction in antibody production is observed involving the primary immune response alone. Transmission electronic microscopy seems to show that melatonin affects the reticulo-epithelial (REp) cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0258-851X
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
507-12
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Changes in the chicken bursa of Fabricius and immune response after treatment with melatonin.
pubmed:affiliation
Chair of Histology and General Embryology, Institute of Anatomy, University of Pisa, Italy.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't