Source:http://linkedlifedata.com/resource/pubmed/id/14575917
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2003-10-24
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pubmed:abstractText |
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system with complex genetic background. In the present study, based in the Finnish population, we typed a large number of microsatellite markers in separately pooled DNA samples from 195 MS patients and 205 controls. A total of 108 markers showed evidence of association. Five genomic regions containing two or more of these markers within a 1-Mb interval were identified, 1q43, 2p16, 4p15, 4q34 and 6p21 (the MHC region). Substantial overlap with previously published linkage genome screens is also seen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0165-5728
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
143
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
70-3
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14575917-Alleles,
pubmed-meshheading:14575917-Case-Control Studies,
pubmed-meshheading:14575917-Female,
pubmed-meshheading:14575917-Finland,
pubmed-meshheading:14575917-Gene Frequency,
pubmed-meshheading:14575917-Genome, Human,
pubmed-meshheading:14575917-Genotype,
pubmed-meshheading:14575917-Humans,
pubmed-meshheading:14575917-Male,
pubmed-meshheading:14575917-Microsatellite Repeats,
pubmed-meshheading:14575917-Multiple Sclerosis,
pubmed-meshheading:14575917-Physical Chromosome Mapping,
pubmed-meshheading:14575917-Polymerase Chain Reaction
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pubmed:year |
2003
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pubmed:articleTitle |
A whole genome association study in Finnish multiple sclerosis patients with 3669 markers.
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pubmed:affiliation |
Turku Immunology Center and Department of Virology, University of Turku, Kiinamyllynkatu 13, FIN 20520 Turku, Finland. miklaa@utu.fi
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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