Source:http://linkedlifedata.com/resource/pubmed/id/14575674
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2003-10-24
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pubmed:abstractText |
The hsp60 expression pattern and catalase activity in the freshwater planarian Dugesia schubarti exposed to copper under laboratory conditions were investigated. In the hsp60 induction experiments, planarians were exposed to a range of copper concentrations (0-960 microgCu/L) for 4 or 24h, to concentrations of 50 or 100 microgCu/L for 2, 4, 8, and 24h at 19 degrees C, and to heat shock at 27 degrees C for 24h. The concentrations of hsp60 in whole-body homogenates were determined immunochemically by Western blotting. Stress protein induction was detected only after 24h treatment at 27 degrees C. The tissue concentration of hsp60 remained unaltered in Cu-exposed planarians under the experimental conditions used. Catalase activity was significantly induced at concentrations of 40, 80, and 160 microgCu/L after 24h exposure. Our results suggest that catalase levels in planarians could represent biomarkers of interest for the estimation of copper effects in freshwater ecosystems.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers,
http://linkedlifedata.com/resource/pubmed/chemical/Catalase,
http://linkedlifedata.com/resource/pubmed/chemical/Chaperonin 60,
http://linkedlifedata.com/resource/pubmed/chemical/Copper,
http://linkedlifedata.com/resource/pubmed/chemical/Heat-Shock Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Water Pollutants
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0147-6513
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
351-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14575674-Animals,
pubmed-meshheading:14575674-Biological Markers,
pubmed-meshheading:14575674-Catalase,
pubmed-meshheading:14575674-Chaperonin 60,
pubmed-meshheading:14575674-Copper,
pubmed-meshheading:14575674-Dose-Response Relationship, Drug,
pubmed-meshheading:14575674-Ecosystem,
pubmed-meshheading:14575674-Environmental Monitoring,
pubmed-meshheading:14575674-Heat-Shock Proteins,
pubmed-meshheading:14575674-Planarians,
pubmed-meshheading:14575674-Water Pollutants
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pubmed:year |
2003
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pubmed:articleTitle |
Stress protein response and catalase activity in freshwater planarian Dugesia (Girardia) schubarti exposed to copper.
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pubmed:affiliation |
Departamento de Biofísica, Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul (UFRGS), RS 91507-970, Porto Alegre, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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