Source:http://linkedlifedata.com/resource/pubmed/id/14575649
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2003-10-24
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pubmed:abstractText |
A general model for the ontogenetic growth of living organisms has been recently proposed. Here we investigate the extension of this model to the growth of solid malignant tumors. A variety of in vitro and in vivo data are analysed and compared with the prediction of a "universal" law, relating properly rescaled tumor masses and tumor growth times. The results support the notion that tumor growth follows such a universal law. Several important implications of this finding are discussed, including its relevance for tumor metastasis and recurrence, cell turnover rates, angiogenesis and invasion.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-5193
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
225
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14575649-Animals,
pubmed-meshheading:14575649-Cell Division,
pubmed-meshheading:14575649-Computational Biology,
pubmed-meshheading:14575649-Humans,
pubmed-meshheading:14575649-Lymphatic Metastasis,
pubmed-meshheading:14575649-Models, Biological,
pubmed-meshheading:14575649-Neoplasm Invasiveness,
pubmed-meshheading:14575649-Neoplasm Recurrence, Local,
pubmed-meshheading:14575649-Neoplasms,
pubmed-meshheading:14575649-Neovascularization, Pathologic
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pubmed:year |
2003
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pubmed:articleTitle |
Does tumor growth follow a "universal law"?
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pubmed:affiliation |
Dip. Neuroscience, Universita di Torino, C. Raffaello 30, 10125, Torino, Italy. caterina.guiot@unito.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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