Linked Life Data

14575270

Source:http://linkedlifedata.com/resource/pubmed/id/14575270

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-10-24
pubmed:abstractText
It is well known that teeth do not erupt in microphthalmic (mi/mi) mice, a type of osteopetrotic mice, due to bone resorption failure. Therefore, we surmise that the masticatory function of these mice is different from that of normal mice. In this study, the differences to the properties of masseter muscle fibers were clarified morphologically and immunohistochemically in the mi/mi and normal mice. Morphological observations revealed that the muscle fibers in the mi/mi mice were smaller than those in normal mice at 9 weeks of age. However, no marked differences between mi/mi and normal mice at 2 and 4 weeks of age. Immunohistochemical observations showed myosin heavy chain (MHC) slow type fibers, which were usually seen at only early stages of development, in 4-week old mi/mi mice. There were also differences in isoform compositions between the mi/mi and normal mice. These results suggest that differences in masticatory function affect the properties of its muscle fibers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0940-9602
pubmed:author
pubmed:issnType
Print
pubmed:volume
185
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
435-40
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Masticatory function and properties of masseter muscle fibers in microphthalmic (mi/mi) mice during postnatal development.
pubmed:affiliation
Tokyo Dental College Department of Anatomy, 1-2-2 Masago, Mihama-ku, Chiba-shi, Chiba, 261-8502 Japan. doi@tdc.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't