|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001973,
umls-concept:C0009488,
umls-concept:C0012634,
umls-concept:C0017431,
umls-concept:C0031437,
umls-concept:C0170657,
umls-concept:C0205217,
umls-concept:C0439793,
umls-concept:C0439861,
umls-concept:C0597357,
umls-concept:C1263846,
umls-concept:C1705241,
umls-concept:C1705242
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2003-10-23
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|
pubmed:abstractText |
Nearly 50% of subjects with continuing symptoms of attention-deficit hyperactivity disorder (ADHD) in adulthood have been reported to show a comorbid substance use disorder. Both ADHD and alcohol dependence have a high genetic load and might even share overlapping sources of genetic liability. Recently, the functional relevant polymorphism within the promoter region of the serotonin transporter gene (5-HTT) and the 5-hydroxytryptamine-2c (5-HT2c) receptor Cys23Ser have been proposed as candidate genes for both entities.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
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pubmed:issn |
0145-6008
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1527-34
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14574222-Adolescent,
pubmed-meshheading:14574222-Adult,
pubmed-meshheading:14574222-Aged,
pubmed-meshheading:14574222-Alcoholism,
pubmed-meshheading:14574222-Antisocial Personality Disorder,
pubmed-meshheading:14574222-Attention Deficit Disorder with Hyperactivity,
pubmed-meshheading:14574222-Carrier Proteins,
pubmed-meshheading:14574222-Comorbidity,
pubmed-meshheading:14574222-Diagnosis, Dual (Psychiatry),
pubmed-meshheading:14574222-Female,
pubmed-meshheading:14574222-Genotype,
pubmed-meshheading:14574222-Humans,
pubmed-meshheading:14574222-Male,
pubmed-meshheading:14574222-Membrane Glycoproteins,
pubmed-meshheading:14574222-Membrane Transport Proteins,
pubmed-meshheading:14574222-Middle Aged,
pubmed-meshheading:14574222-Nerve Tissue Proteins,
pubmed-meshheading:14574222-Phenotype,
pubmed-meshheading:14574222-Receptor, Serotonin, 5-HT2C,
pubmed-meshheading:14574222-Serotonin Plasma Membrane Transport Proteins
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pubmed:year |
2003
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|
pubmed:articleTitle |
Comorbidity of alcohol dependence with attention-deficit hyperactivity disorder: differences in phenotype with increased severity of the substance disorder, but not in genotype (serotonin transporter and 5-hydroxytryptamine-2c receptor).
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pubmed:affiliation |
Department of Psychiatry, University of Regensburg, Regensburg, Germany. monika.johann@bzk.uni-regensburg.de
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
