Linked Life Data

14572913

Source:http://linkedlifedata.com/resource/pubmed/id/14572913

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-10-23
pubmed:abstractText
In vertebrates, elaborate cellular interactions regulate the establishment of the complex structural pattern of the developing central nervous system. Distinct neural and glial identities are acquired by neuroepithelial cells, through progressive restriction of histogenetic potential under the influence of local environmental signals. The localization of the sources of such morphogenetic signals in discrete domains of the developing neural primordium has led to the concept of secondary organizers which refine the identity and polarity of neighboring neuroepithelial regions. Thus, these organizers, secondary to those that operate throughout the embryo during gastrulation, act to pattern the anterior neural plate and tube giving rise to the forebrain, midbrain and hindbrain vesicles. Important progress has recently been made in understanding their genesis and function.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:author
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-91
pubmed:dateRevised
2007-2-26
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Neuroepithelial secondary organizers and cell fate specification in the developing brain.
pubmed:affiliation
Fac. de Medicina, Instituto de Neurociencias UMH-CSIC, University Miguel Hernandez, Carretera de Valencia, N-332, Km 87, E-03550, San Juan Alicante, Spain. diegoaza@umh.es
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't