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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2003-10-22
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pubmed:abstractText |
and aims: In neonates the gastrointestinal tract is exposed to food and bacterial antigens at a time when the gut mucosal immune system has not developed the ability to induce oral tolerance. This increases the risk for an inappropriate immune response to oral antigens. Transforming growth factor beta (TGF-beta) is an immunoregulatory cytokine present in high concentration in maternal milk. Interleukin 18 (IL-18) is a cytokine that mediates early immune events, and drives T cell development. We assessed the role of TGF-beta in mediating mucosal immune development and specifically the effect on endogenous IL-18.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10359906,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10438973,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10449160,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10469336,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10491411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10554123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10590020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10611756,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10923599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-10941968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11007972,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11093129,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11173908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11312119,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11380683,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11477400,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11477409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-11489954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-1588275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-1834576,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-2085099,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-2503151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-2563456,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-3192037,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-6332297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-7529282,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-8009224,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-8403511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-8429522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-8666919,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-9232828,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-9353156,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-9586760,
http://linkedlifedata.com/resource/pubmed/commentcorrection/14570726-9773841
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0017-5749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1579-86
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:14570726-Animals,
pubmed-meshheading:14570726-Animals, Suckling,
pubmed-meshheading:14570726-Antigens, CD,
pubmed-meshheading:14570726-Blotting, Western,
pubmed-meshheading:14570726-Cell Count,
pubmed-meshheading:14570726-Dendritic Cells,
pubmed-meshheading:14570726-Down-Regulation,
pubmed-meshheading:14570726-Eosinophils,
pubmed-meshheading:14570726-Female,
pubmed-meshheading:14570726-Fluorescent Antibody Technique,
pubmed-meshheading:14570726-Ileum,
pubmed-meshheading:14570726-Interleukin-18,
pubmed-meshheading:14570726-Intestinal Mucosa,
pubmed-meshheading:14570726-Intestine, Small,
pubmed-meshheading:14570726-Lymphocyte Activation,
pubmed-meshheading:14570726-Mast Cells,
pubmed-meshheading:14570726-Milk,
pubmed-meshheading:14570726-RNA, Messenger,
pubmed-meshheading:14570726-Rats,
pubmed-meshheading:14570726-Rats, Wistar,
pubmed-meshheading:14570726-Transforming Growth Factor beta,
pubmed-meshheading:14570726-Up-Regulation
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pubmed:year |
2003
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pubmed:articleTitle |
Maternal milk regulation of cell infiltration and interleukin 18 in the intestine of suckling rat pups.
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pubmed:affiliation |
Child Health Research Institute, North Adelaide, SA 5006, Australia. irmeli.pentila@adelaide.edu.au
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pubmed:publicationType |
Journal Article
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