rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
1993-1-7
|
pubmed:abstractText |
The clinical efficacy of aclarubicin, an anthracycline antibiotic, was studied in 48 patients with leukemia. The antibiotic was used in the following combinations with cytarabine: "7 + 7", "5 + 5" and "7 & 3". A complete remission was stated in 14 (42.4 per cent) out of 33 patients with acute nonlymphoid leukemia, 6 (43 per cent) out of the 14 patients having relapses. The combined therapy was effective in 4 out of 5 pre-resistant patients. The "7 + 3" scheme was the most beneficial. The most common adverse reactions were nausea and vomiting.
|
pubmed:language |
rus
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0235-2990
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
37
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
47-9
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1456812-Aclarubicin,
pubmed-meshheading:1456812-Adult,
pubmed-meshheading:1456812-Aged,
pubmed-meshheading:1456812-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1456812-Blast Crisis,
pubmed-meshheading:1456812-Cytarabine,
pubmed-meshheading:1456812-Humans,
pubmed-meshheading:1456812-Leukemia,
pubmed-meshheading:1456812-Leukemia, Monocytic, Acute,
pubmed-meshheading:1456812-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:1456812-Leukemia, Myeloid, Acute,
pubmed-meshheading:1456812-Leukemia, Myelomonocytic, Acute,
pubmed-meshheading:1456812-Middle Aged,
pubmed-meshheading:1456812-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:1456812-Remission Induction
|
pubmed:year |
1992
|
pubmed:articleTitle |
[Experience with using aclarubicin in the treatment of acute leukemia and blast crisis of chronic myeloid leukemia].
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Controlled Clinical Trial
|