Linked Life Data

14567710

Source:http://linkedlifedata.com/resource/pubmed/id/14567710

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2003-10-21
pubmed:abstractText
The mercury(II)-mediated electrophilic ring-opening reaction of various cyclopropylcarbinol derivatives bearing adjacent stereocenters and a remote nucleophilic functional group provides a useful strategy for synthesizing compounds bearing several contiguous stereocenters. These highly diastereoselective reactions occur with anchimeric assistance by the internal nucleophilic moiety and afford synthetically valuable building blocks such as polypropionate units or heterocyclic compounds. The application of cyclopropylcarbinol ring-opening for the preparation of functionalized oxygen heterocycles in natural product synthesis is also outlined.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Oct
pubmed:issn
0001-4842
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
766-72
pubmed:year
2003
pubmed:articleTitle
Stereoselective synthesis of polypropionate units and heterocyclic compounds by cyclopropylcarbinol ring-opening with mercury(II) salts.
pubmed:affiliation
Laboratoire de Chimie Organique, associé au CNRS, ESPCI, 10 rue Vauquelin 75231 Paris Cedex 05, France.
pubmed:publicationType
Journal Article