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pubmed:abstractText |
Survivin, one of the apoptosis inhibitor proteins, has been detected in most cancers in humans. In addition, two splice variants (survivin-2B and survivin-deltaEx3) have been identified. The authors investigated the transcription levels of survivin messenger (m)RNA and its splice variants in nine tumor cell lines, including gliomas, and in 25 brain tumor samples, by performing quantitative reverse transcription-polymerase chain reaction. The correlation between transcript expression levels and pathological findings were also analyzed.
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pubmed:affiliation |
Department of Neurosurgery, Central Clinical Laboratory, Osaka Medical College, Takatsuki City, Osaka, Japan.
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