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pubmed-article:14565441pubmed:abstractTextThe synthesis of 3'- and 5'-O-levulinyl nucleosidic monomers through enzymatic acylation with acetonoxime levulinate is demonstrated. The acylation process takes place in one-step and use of expensive reagents, such as DMTrCl is avoided. The regioselectivity of the procedure makes it very convenient for acylated monomers required for solution phase synthesis of oligonucleotides.lld:pubmed
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pubmed-article:14565441pubmed:articleTitleDirect regioselective enzymatic acylation of nucleosides: building-blocks for the solution phase synthesis of oligonucleotides.lld:pubmed
pubmed-article:14565441pubmed:affiliationDepartamento de Química Orgánica e Inorgánica, Facultad de Química, Universidad de Oviedo, Oviedo, Spain.lld:pubmed
pubmed-article:14565441pubmed:publicationTypeJournal Articlelld:pubmed