rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2003-10-17
|
pubmed:abstractText |
The evolutionarily ancient intracellular stress response protects cells from the effects of external and internal forces which perturb cellular metabolism. Members of the major histocompatibility complex (MHC) class I-like superfamily act as cell surface indicators of the intracellular stress response. Cellular immunity employs these indicators as a cue for elimination of damaged, infected, and malignant cells, promoting the health of the individual and the evolutionary success of the species.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1074-7613
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
19
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
469-77
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:14563312-Animals,
pubmed-meshheading:14563312-Biological Markers,
pubmed-meshheading:14563312-Chaperonin 60,
pubmed-meshheading:14563312-Evolution, Molecular,
pubmed-meshheading:14563312-Histocompatibility Antigens Class I,
pubmed-meshheading:14563312-Humans,
pubmed-meshheading:14563312-Mice,
pubmed-meshheading:14563312-Multigene Family,
pubmed-meshheading:14563312-Receptors, Immunologic,
pubmed-meshheading:14563312-Receptors, Natural Killer Cell,
pubmed-meshheading:14563312-T-Lymphocytes
|
pubmed:year |
2003
|
pubmed:articleTitle |
Stress management: MHC class I and class I-like molecules as reporters of cellular stress.
|
pubmed:affiliation |
Program in Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.
|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|