Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2004-7-26
pubmed:abstractText
The effects on spontaneous ovulation associated with the unilateral or bilateral sectioning of the superior ovarian nerves (SON) were analyzed in guinea pigs at different time intervals of the estrous cycle. Day 1 of the estrous cycle was defined as the day when the animal presents complete loss of the vaginal membrane (open vagina). Subsequent phases of the cycle were determined by counting the days after Day 1. All animals were autopsied on the fifth day of the estrous cycle after surgery. Sectioning the right, left, or both SONs on day 5 (early luteal phase) resulted in a significant increase in the number of fresh corpora lutea. Ovulation increased significantly when the left SON (L-SON) was sectioned during late follicular phase (day 1) and medium luteal phase (day 8). When surgery was performed on days 1 or 8, neither sectioning the right SON (R-SON) nor sectioning the SON bilaterally had an apparent effect on ovulation rates. Similarly, ovulation rates were not affected when unilateral (right or left) or bilateral sectioning of the SON was performed during late luteal phase two (day 12). Unilateral or bilateral sectioning of the SON performed during the early luteal phase (day 5) was associated with a significant decrease in uterine weight. A comparable effect was observed when the L-SON was sectioned during late follicular phase (day 1), or medium luteal phase (day 8). No effects on uterine weight were observed when unilateral or bilateral sectioning of the SON was performed during late luteal phase. Our results suggest that in the guinea pig the SON modulates ovulation, and that the degree of modulation varies along the estrous cycle. The strongest influence of the SONs on ovulation occurs during early luteal phase, and decrease thereafter, being absent by late luteal phase. In addition, sectioning the left or the right SON caused different responses by the ovaries of adult guinea pigs. This paper discusses the mechanisms by which ovulation increased when the SON was surgically cut.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-1206274, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-12225769, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-2426085, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-2454745, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-3350470, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-3512260, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-4067920, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-5016505, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-6325133, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-7191901, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-7416501, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-790424, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-8169555, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-9496238, http://linkedlifedata.com/resource/pubmed/commentcorrection/14561223-9771465
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1477-7827
pubmed:author
pubmed:issnType
Electronic
pubmed:day
25
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
The effects of superior ovarian nerve sectioning on ovulation in the guinea pig.
pubmed:affiliation
Facultad de Ciencias Químicas, Universidad Autónoma de Puebla, México. flunam@yahoo.com.mx
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't