Source:http://linkedlifedata.com/resource/pubmed/id/14559160
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2003-10-15
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pubmed:abstractText |
Biochemical changes in rat brain acetylcholinesterase (AChE) activity and molecular isoform distribution were studied using the middle cerebral artery occlusion model. After 24 h of permanent focal ischemia, AChE specific activity from infarcted cortex was found to decrease compared with contralateral cortex. Also a decrease in the minor monomeric (G1) form of AChE is response to ischemia was observed. Ischemia-induced AChE decrease was partially diminished by pre-treatment with dizocilpine (MK-801), a neuroprotective NMDA receptor blocker.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0169-328X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
240-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14559160-Acetylcholinesterase,
pubmed-meshheading:14559160-Animals,
pubmed-meshheading:14559160-Brain,
pubmed-meshheading:14559160-Brain Chemistry,
pubmed-meshheading:14559160-Brain Ischemia,
pubmed-meshheading:14559160-Dizocilpine Maleate,
pubmed-meshheading:14559160-Functional Laterality,
pubmed-meshheading:14559160-Male,
pubmed-meshheading:14559160-Neuroprotective Agents,
pubmed-meshheading:14559160-Protein Isoforms,
pubmed-meshheading:14559160-Rats,
pubmed-meshheading:14559160-Rats, Inbred F344
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pubmed:year |
2003
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pubmed:articleTitle |
Acetylcholinesterase activity and molecular isoform distribution are altered after focal cerebral ischemia.
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pubmed:affiliation |
Instituto de Neurociencias, Universidad Miguel Hernández, San Juan de Alicante, Spain.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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