Source:http://linkedlifedata.com/resource/pubmed/id/14555589
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-10-13
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pubmed:abstractText |
Pentoxifylline (POF) has been shown to suppress the cytokine production from lipopolysaccharide (LPS)-stimulated monocytes/alveolar macrophages (AMs). Sarcoidosis is a granulomatous disease that is driven by the action of tumor necrosis factor (TNF)-alpha and other proinflammatory cytokines. In this study, we aimed to investigate the effects of POF on the production of TNF-alpha, interleukin (IL)-1 beta, IL-6, IL-8, IL-10, and the soluble TNF receptors (sTNFRs) 1 and 2 from AMs in sarcoidosis, and we also compared them with those of dexamethasone (DEX).
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0012-3692
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1526-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14555589-Adult,
pubmed-meshheading:14555589-Anti-Inflammatory Agents,
pubmed-meshheading:14555589-Cytokines,
pubmed-meshheading:14555589-Dexamethasone,
pubmed-meshheading:14555589-Female,
pubmed-meshheading:14555589-Humans,
pubmed-meshheading:14555589-Macrophages, Alveolar,
pubmed-meshheading:14555589-Male,
pubmed-meshheading:14555589-Middle Aged,
pubmed-meshheading:14555589-Pentoxifylline,
pubmed-meshheading:14555589-Sarcoidosis, Pulmonary
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pubmed:year |
2003
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pubmed:articleTitle |
Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline: comparison with dexamethasone.
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pubmed:affiliation |
Department of Pneumology and Allergy, Ruhrlandklinik, Medical Faculty, University of Essen, Essen, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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