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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2003-10-13
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pubmed:abstractText |
A series of 7-acyloxymethylcamptothecin and 20-O-acyl-7-acyloxymethylcamptothecin derivatives were regioselectively prepared on different solvents. 7-Acyloxymethylcamptothecins possess more efficacy than 20-O-acyl-7-acyloxymethylcamptothecins against six human cancer cell lines in vitro.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3739-41
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14552770-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:14552770-Camptothecin,
pubmed-meshheading:14552770-Cell Line, Tumor,
pubmed-meshheading:14552770-Drug Screening Assays, Antitumor,
pubmed-meshheading:14552770-Humans,
pubmed-meshheading:14552770-Indicators and Reagents,
pubmed-meshheading:14552770-Magnetic Resonance Spectroscopy,
pubmed-meshheading:14552770-Solvents,
pubmed-meshheading:14552770-Structure-Activity Relationship
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pubmed:year |
2003
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pubmed:articleTitle |
Regioselective synthesis and cytotoxicities of camptothecin derivatives modified at the 7-, 10- and 20-positions.
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pubmed:affiliation |
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. xdp@imm.ac.cn
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pubmed:publicationType |
Journal Article
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