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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2003-10-10
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pubmed:abstractText |
We conducted the present study to determine which of the 4 components of breast milk (whole milk, skim milk, lipid layer, and breast-milk cells) had the highest sensitivity and concentration of human immunodeficiency virus (HIV) type 1 RNA burden and to determine biological correlates to these factors. The probability of detection of HIV (sensitivity) and the concentration of HIV-1 RNA were both associated with the choice of milk component, CD4(+) cell count, concentration of blood serum HIV-1 RNA, and the presence of breast inflammation. Whole milk demonstrated higher sensitivity and mean concentration than any other single component. Sensitivity was enhanced by analyzing all 4 components of breast milk.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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|
pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:BandaTopiaT,
pubmed-author:ChilongoziDavid ADA,
pubmed-author:CohenMyron SMS,
pubmed-author:DzinyembaWillardW,
pubmed-author:FiscusSusan ASA,
pubmed-author:HoffmanIrving FIF,
pubmed-author:JoshiPriyaP,
pubmed-author:KazembePeter NPN,
pubmed-author:LeuSzu-YunSY,
pubmed-author:MartinsonFrancis E AFE,
pubmed-author:StewartPaul WPW
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pubmed:issnType |
Print
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|
pubmed:day |
15
|
|
pubmed:volume |
188
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1209-12
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:14551892-Adult,
pubmed-meshheading:14551892-Female,
pubmed-meshheading:14551892-HIV Infections,
pubmed-meshheading:14551892-HIV-1,
pubmed-meshheading:14551892-Humans,
pubmed-meshheading:14551892-Infectious Disease Transmission, Vertical,
pubmed-meshheading:14551892-Lactation,
pubmed-meshheading:14551892-Mastitis,
pubmed-meshheading:14551892-Milk, Human,
pubmed-meshheading:14551892-Pilot Projects,
pubmed-meshheading:14551892-RNA, Viral,
pubmed-meshheading:14551892-Sensitivity and Specificity,
pubmed-meshheading:14551892-Viral Load
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pubmed:year |
2003
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pubmed:articleTitle |
Human immunodeficiency virus type 1 RNA in breast-milk components.
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pubmed:affiliation |
Center for Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina 27599-7030, USA. hoffmani@med.unc.edu.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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