|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007610,
umls-concept:C0018270,
umls-concept:C0026844,
umls-concept:C0031727,
umls-concept:C0040715,
umls-concept:C0052193,
umls-concept:C0521119,
umls-concept:C0599718,
umls-concept:C0599813,
umls-concept:C0599893,
umls-concept:C0851285,
umls-concept:C1135918,
umls-concept:C1292733,
umls-concept:C1522702,
umls-concept:C1710082
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2003-12-15
|
|
pubmed:abstractText |
Elevated apolipoprotein D (apoD) levels are associated with reduced proliferation of cancer cells. We therefore investigated whether apoD, which occurs free or associated with HDL, suppresses vascular smooth muscle cell (VSMC) proliferation, which is related to the pathobiology of disease.
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|
pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1524-4636
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
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pubmed:volume |
23
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2172-7
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|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:14551159-Animals,
pubmed-meshheading:14551159-Aorta,
pubmed-meshheading:14551159-Apolipoproteins,
pubmed-meshheading:14551159-Apolipoproteins D,
pubmed-meshheading:14551159-Arteriosclerosis,
pubmed-meshheading:14551159-Cell Division,
pubmed-meshheading:14551159-Cells, Cultured,
pubmed-meshheading:14551159-Coronary Vessels,
pubmed-meshheading:14551159-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:14551159-Mitogen-Activated Protein Kinase 3,
pubmed-meshheading:14551159-Mitogen-Activated Protein Kinases,
pubmed-meshheading:14551159-Muscle, Smooth, Vascular,
pubmed-meshheading:14551159-Phosphorylation,
pubmed-meshheading:14551159-Platelet-Derived Growth Factor,
pubmed-meshheading:14551159-Protein Transport,
pubmed-meshheading:14551159-RNA, Messenger,
pubmed-meshheading:14551159-Rats,
pubmed-meshheading:14551159-Sheep,
pubmed-meshheading:14551159-Transfection
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|
pubmed:year |
2003
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|
pubmed:articleTitle |
Apolipoprotein D inhibits platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferated by preventing translocation of phosphorylated extracellular signal regulated kinase 1/2 to the nucleus.
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|
pubmed:affiliation |
Cardiovascular Research Program, The Hospital for Sick Children, and the Department of Pediatrics, University of Toronto.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
