| pubmed-article:14536089 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14536089 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:14536089 | lifeskim:mentions | umls-concept:C0007709 | lld:lifeskim |
| pubmed-article:14536089 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:14536089 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:14536089 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:14536089 | pubmed:dateCreated | 2003-10-10 | lld:pubmed |
| pubmed-article:14536089 | pubmed:abstractText | Recent data in yeast and Drosophila suggest a domain-like centromere structure with a modified chromatin core and flanking regions of heterochromatin. We have analyzed a functional human centromere and defined a region of increased chromosome scaffold/matrix attachment that overlaps three other distinct and nonoverlapping domains for constitutive centromere proteins CENP-A and CENP-H, and heterochromatin protein HP1. Transcriptional competency is intact throughout the S/MAR-enriched region and within the CENP-A- and CENP-H-associated chromatin. These results provide insights into the relationship between centromeric chromatin and transcriptional competency in vivo, highlighting the permissibility of transcription within the constitutively modified, nonheterochromatic chromatin of a functional eukaryotic centromere. | lld:pubmed |
| pubmed-article:14536089 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:14536089 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:14536089 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14536089 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:14536089 | pubmed:issn | 1097-2765 | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:SafferyRichar... | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:ChooK H... | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:WongLee HLH | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:AndersonMelis... | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:TodokoroKazuo... | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:CraigJeffrey... | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:SumerHuseyinH | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:HassanSaraS | lld:pubmed |
| pubmed-article:14536089 | pubmed:author | pubmed-author:StaffordAngel... | lld:pubmed |
| pubmed-article:14536089 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14536089 | pubmed:volume | 12 | lld:pubmed |
| pubmed-article:14536089 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14536089 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14536089 | pubmed:pagination | 509-16 | lld:pubmed |
| pubmed-article:14536089 | pubmed:dateRevised | 2008-9-11 | lld:pubmed |
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| pubmed-article:14536089 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:14536089 | pubmed:articleTitle | Transcription within a functional human centromere. | lld:pubmed |
| pubmed-article:14536089 | pubmed:affiliation | The Murdoch Childrens Research Institute, Royal Children's Hospital, Flemington Road, Melbourne, 3052, Australia. | lld:pubmed |
| pubmed-article:14536089 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14536089 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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