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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
21
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pubmed:dateCreated |
2003-10-10
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pubmed:abstractText |
The proposed structure of lasonolide A was synthesized employing radical cyclization reactions of beta-alkoxyacrylates for preparation of the tetrahydropyranyl units A and B, but the spectroscopic data did not match those of the natural product. Both enantiomers of a revised structure featuring 17E,25Z double bonds were synthesized, and the (-)-isomer was found to be the biologically active enantiomer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-3263
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pubmed:author |
pubmed-author:HongChang YongCY,
pubmed-author:JeonKiwanK,
pubmed-author:JeongShinWuS,
pubmed-author:JooJung MinJM,
pubmed-author:JungCheol-KyuCK,
pubmed-author:KangJung WonJW,
pubmed-author:KimDae-ShikDS,
pubmed-author:KwakHyo ShinHS,
pubmed-author:LeeEunE,
pubmed-author:ParkJi HyunJH,
pubmed-author:ParkJin HyunJH,
pubmed-author:SongHo YoungHY
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pubmed:issnType |
Print
|
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pubmed:day |
17
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pubmed:volume |
68
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
8080-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
|
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pubmed:year |
2003
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pubmed:articleTitle |
Lasonolide A: structural revision and total synthesis.
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|
pubmed:affiliation |
School of Chemistry and Molecular Engineering, Seoul National University, Seoul 151-747, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
