Linked Life Data

1453500

Source:http://linkedlifedata.com/resource/pubmed/id/1453500

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-12-31
pubmed:abstractText
The role of mast cells (MC) in the development of liver fibrosis during experimental hepatocarcinogenesis in rats has been studied light microscopically, histochemically and electron microscopically. An increase in the number of MC in the proliferated connective tissue was found. The histochemical examination showed that the increased MC almost exclusively were connective tissue mast cells (CTMC), whilst mucosa mast cells (MMC) were only rarely seen. The electron microscopical observation revealed a close topographical relationship between MC and fibroblasts sending out pseudopodia, which encircled granula released from MC and phagocytized them. The fibroblasts with phagocytized MC granules were markedly activated showing enhanced formation of collagenous fibrils. Finally, the role of MC in the development of liver fibrosis is discussed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0257-716X
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
129-33
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
[Role of mast cells in the development of liver fibrosis during experimental hepatocarcinogenesis in rats].
pubmed:affiliation
Abteilung für Ultrastrukturelle Pathologie, Tongji Medizinische Universität, Wuhan.
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't