|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2003-10-8
|
|
pubmed:abstractText |
Recent studies have demonstrated that c-Cbl functions as a ubiquitin-protein ligase toward immune receptors and non-receptor protein-tyrosine kinase Syk by facilitating their ubiquitination and subsequent targeting to proteasomes. However, it was not clear whether Src family kinase Lyn is regulated by the Cbl family of ubiquitin-protein ligases.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1356-9597
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
825-36
|
|
pubmed:dateRevised |
2011-11-2
|
|
pubmed:meshHeading |
pubmed-meshheading:14531861-Animals,
pubmed-meshheading:14531861-COS Cells,
pubmed-meshheading:14531861-Cell Line, Tumor,
pubmed-meshheading:14531861-Cercopithecus aethiops,
pubmed-meshheading:14531861-Enzyme Activation,
pubmed-meshheading:14531861-Gene Expression Regulation,
pubmed-meshheading:14531861-Leukemia, Basophilic, Acute,
pubmed-meshheading:14531861-Mast Cells,
pubmed-meshheading:14531861-Phosphorylation,
pubmed-meshheading:14531861-Precipitin Tests,
pubmed-meshheading:14531861-Proto-Oncogene Proteins,
pubmed-meshheading:14531861-Rats,
pubmed-meshheading:14531861-Receptors, IgE,
pubmed-meshheading:14531861-Tyrosine,
pubmed-meshheading:14531861-Ubiquitin,
pubmed-meshheading:14531861-beta-N-Acetylhexosaminidases,
pubmed-meshheading:14531861-src-Family Kinases
|
|
pubmed:year |
2003
|
|
pubmed:articleTitle |
Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation.
|
|
pubmed:affiliation |
Division of Proteomics, Department of Genome Sciences, Kobe University Graduate School of Medicine, Kobe, Japan.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
