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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-10-8
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pubmed:abstractText |
During transcription elongation, RNA polymerase II is arrested on the template when incorrect ribonucleotides are incorporated into the nascent transcripts. Transcription factor S-II enhances the excision of these mis-incorporated nucleotides by RNA polymerase II and stimulates transcription elongation in vitro. This mechanism is considered to be transcriptional proof-reading, but its physiological relevance remains unknown.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1356-9597
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
779-88
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14531857-Acetylcysteine,
pubmed-meshheading:14531857-Antioxidants,
pubmed-meshheading:14531857-Gene Expression Regulation, Fungal,
pubmed-meshheading:14531857-Genes, Fungal,
pubmed-meshheading:14531857-Genes, Reporter,
pubmed-meshheading:14531857-Lac Operon,
pubmed-meshheading:14531857-Mutation,
pubmed-meshheading:14531857-Operon,
pubmed-meshheading:14531857-Oxidants,
pubmed-meshheading:14531857-Oxidative Stress,
pubmed-meshheading:14531857-RNA Polymerase II,
pubmed-meshheading:14531857-Saccharomyces cerevisiae,
pubmed-meshheading:14531857-Transcription, Genetic,
pubmed-meshheading:14531857-Transcription Factors,
pubmed-meshheading:14531857-beta-Galactosidase
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pubmed:year |
2003
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pubmed:articleTitle |
Transcription elongation factor S-II maintains transcriptional fidelity and confers oxidative stress resistance.
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pubmed:affiliation |
Department of Developmental Biochemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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