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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-10-8
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pubmed:abstractText |
X-linked Alport syndrome is a progressive nephritis caused by mutations of the COL4A5 gene. This gene encodes the collagen alpha 5(IV) chain, which is abnormally distributed in the glomerular basement membrane (GBM) and epidermal basement membrane (EBM). It has been reported a negative correlation between alpha 5(IV) chain distribution in EBM and the degree of proteinuria in heterozygous females with Alport syndrome.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1787-91
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pubmed:dateRevised |
2006-5-12
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pubmed:meshHeading |
pubmed-meshheading:14531812-Adolescent,
pubmed-meshheading:14531812-Adult,
pubmed-meshheading:14531812-Aged,
pubmed-meshheading:14531812-Basement Membrane,
pubmed-meshheading:14531812-Child,
pubmed-meshheading:14531812-Child, Preschool,
pubmed-meshheading:14531812-Cohort Studies,
pubmed-meshheading:14531812-Collagen Type IV,
pubmed-meshheading:14531812-Female,
pubmed-meshheading:14531812-Humans,
pubmed-meshheading:14531812-Kidney Glomerulus,
pubmed-meshheading:14531812-Middle Aged,
pubmed-meshheading:14531812-Nephritis, Hereditary,
pubmed-meshheading:14531812-Pedigree,
pubmed-meshheading:14531812-Proteinuria,
pubmed-meshheading:14531812-Severity of Illness Index
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pubmed:year |
2003
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pubmed:articleTitle |
Epidermal basement membrane alpha 5(IV) expression in females with Alport syndrome and severity of renal disease.
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pubmed:affiliation |
Division of Nephrology and Dialysis, Bambino Gesù Children's Hospital and Research Institute, Rome, Italy. lmassella@opbg.net
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pubmed:publicationType |
Journal Article
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