| pubmed-article:1452651 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1452651 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:1452651 | lifeskim:mentions | umls-concept:C0205281 | lld:lifeskim |
| pubmed-article:1452651 | lifeskim:mentions | umls-concept:C0014323 | lld:lifeskim |
| pubmed-article:1452651 | lifeskim:mentions | umls-concept:C0370215 | lld:lifeskim |
| pubmed-article:1452651 | lifeskim:mentions | umls-concept:C0205210 | lld:lifeskim |
| pubmed-article:1452651 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:1452651 | pubmed:dateCreated | 1993-1-6 | lld:pubmed |
| pubmed-article:1452651 | pubmed:abstractText | Approximately 10% of the world population is infected with Entamoeba histolytica, but only 10% of the carriers develop symptomatic amebiasis. This discrepancy could be explained by the genotypic differences between the morphologically indistinguishable invasive and noninvasive strains of E. histolytica currently identified by zymodeme analysis, a technique that is unsuitable for routine diagnostic laboratories. Here we report the production of a monoclonal antibody against E. histolytica and its use in an immunofluorescence assay to identify invasive isolates cultured from stool samples of infected patients in several regions where amebiasis is endemic: Bangladesh, Colombia, and Mexico. After testing a total of 88 E. histolytica isolates, the correlation between zymodeme characterization and the immunofluorescence assay with the invasive isolate-specific monoclonal antibody was 100%. The epitope detected by the invasive isolate-specific monoclonal antibody resides in a previously undescribed internal protein with molecular masses of 84 and 81 kDa in axenic and polyxenic E. histolytica strains, respectively. | lld:pubmed |
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| pubmed-article:1452651 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1452651 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1452651 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1452651 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1452651 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1452651 | pubmed:issn | 0095-1137 | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:GuhaSS | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:HallAA | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:HaqueRR | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:AguirreAA | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:Ruiz-Palacios... | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:WarhurstD CDC | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:JaramilloCC | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:RehmanTT | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:CastañonGG | lld:pubmed |
| pubmed-article:1452651 | pubmed:author | pubmed-author:Gonzalez-Ruiz... | lld:pubmed |
| pubmed-article:1452651 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1452651 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:1452651 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1452651 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:1452651 | pubmed:pagination | 2807-13 | lld:pubmed |
| pubmed-article:1452651 | pubmed:dateRevised | 2010-9-7 | lld:pubmed |
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| pubmed-article:1452651 | pubmed:meshHeading | pubmed-meshheading:1452651-... | lld:pubmed |
| pubmed-article:1452651 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1452651 | pubmed:articleTitle | A monoclonal antibody for distinction of invasive and noninvasive clinical isolates of Entamoeba histolytica. | lld:pubmed |
| pubmed-article:1452651 | pubmed:affiliation | Department of Medical Parasitology, London School of Hygiene and Tropical Medicine, United Kingdom. | lld:pubmed |
| pubmed-article:1452651 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1452651 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:1452651 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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