pubmed-article:14526407 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:14526407 | lifeskim:mentions | umls-concept:C0006826 | lld:lifeskim |
pubmed-article:14526407 | lifeskim:mentions | umls-concept:C0011065 | lld:lifeskim |
pubmed-article:14526407 | lifeskim:mentions | umls-concept:C0023884 | lld:lifeskim |
pubmed-article:14526407 | lifeskim:mentions | umls-concept:C0597409 | lld:lifeskim |
pubmed-article:14526407 | lifeskim:mentions | umls-concept:C0175673 | lld:lifeskim |
pubmed-article:14526407 | pubmed:issue | 10 | lld:pubmed |
pubmed-article:14526407 | pubmed:dateCreated | 2003-10-3 | lld:pubmed |
pubmed-article:14526407 | pubmed:abstractText | Transplantation of organs procured from donors with malignancies identified subsequent to implantation presents a significant dilemma regarding the optimal management strategy to simultaneously minimize the risk for cancer transmission and recipient morbidity. In this report, we present a patient who underwent orthotopic liver transplantation for hepatitis B cirrhosis. The donor had no previous history of cancer. On autopsy, enlarged mediastinal lymph nodes led to the discovery of a 1-cm lung tumor. Histological examination showed pulmonary adenocarcinoma with metastatic mediastinal disease. Despite urgent retransplantation within 7 days, the recipient developed metastatic pulmonary adenocarcinoma diagnosed 11 months after transplantation and died soon thereafter. Analysis of short tandem repeat regions of chromosomal DNA from the recipient, the 2 liver donors, and the posttransplantation tumor corroborates that the first donor was the source of the malignancy. This case of donor-transmitted malignancy underscores the need for vigilance by the procuring surgeon in identifying potential malignancy during organ retrieval and use of a full autopsy on selected donors after organ procurement. | lld:pubmed |
pubmed-article:14526407 | pubmed:language | eng | lld:pubmed |
pubmed-article:14526407 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:14526407 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:14526407 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:14526407 | pubmed:month | Oct | lld:pubmed |
pubmed-article:14526407 | pubmed:issn | 1527-6465 | lld:pubmed |
pubmed-article:14526407 | pubmed:author | pubmed-author:JonesKirk DKD | lld:pubmed |
pubmed-article:14526407 | pubmed:author | pubmed-author:AscherNancy... | lld:pubmed |
pubmed-article:14526407 | pubmed:author | pubmed-author:LipshutzGeral... | lld:pubmed |
pubmed-article:14526407 | pubmed:author | pubmed-author:FengSandyS | lld:pubmed |
pubmed-article:14526407 | pubmed:author | pubmed-author:Baxter-LoweLe... | lld:pubmed |
pubmed-article:14526407 | pubmed:author | pubmed-author:NguyenTimT | lld:pubmed |
pubmed-article:14526407 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:14526407 | pubmed:volume | 9 | lld:pubmed |
pubmed-article:14526407 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:14526407 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:14526407 | pubmed:pagination | 1102-7 | lld:pubmed |
pubmed-article:14526407 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:14526407 | pubmed:meshHeading | pubmed-meshheading:14526407... | lld:pubmed |
pubmed-article:14526407 | pubmed:meshHeading | pubmed-meshheading:14526407... | lld:pubmed |
pubmed-article:14526407 | pubmed:year | 2003 | lld:pubmed |
pubmed-article:14526407 | pubmed:articleTitle | Death from donor-transmitted malignancy despite emergency liver retransplantation. | lld:pubmed |
pubmed-article:14526407 | pubmed:affiliation | Division of Transplantation, Department of Surgery, University of California, San Francisco, CA 94143, USA. | lld:pubmed |
pubmed-article:14526407 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:14526407 | pubmed:publicationType | Case Reports | lld:pubmed |