Source:http://linkedlifedata.com/resource/pubmed/id/14523213
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-10-2
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pubmed:abstractText |
Fetal hemoglobin (HbF) levels in the hemolysates obtained from infants who died from sudden infant death syndrome (SIDS) are reported to be markedly increased compared with controls. This finding could have been explained by increased HbF synthesis caused by episodes of hypoxemia in the SIDS infants. A prospective study in a group of infants being monitored at home after an apparent life-threatening event (ALTE) and considered at increased risk for SIDS was conducted with an improved ribonuclease protection assay. The ribonuclease protection assay allowed for the quantitation of [gamma/(gamma+beta)]-globin mRNAs, which has a highly significant correlation with the levels of HbF synthesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1098-4275
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e285
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:14523213-Anoxia,
pubmed-meshheading:14523213-Apnea,
pubmed-meshheading:14523213-Biological Markers,
pubmed-meshheading:14523213-Disease Susceptibility,
pubmed-meshheading:14523213-Female,
pubmed-meshheading:14523213-Fetal Hemoglobin,
pubmed-meshheading:14523213-Gene Expression Profiling,
pubmed-meshheading:14523213-Globins,
pubmed-meshheading:14523213-Home Nursing,
pubmed-meshheading:14523213-Humans,
pubmed-meshheading:14523213-Infant,
pubmed-meshheading:14523213-Male,
pubmed-meshheading:14523213-Monitoring, Ambulatory,
pubmed-meshheading:14523213-Prospective Studies,
pubmed-meshheading:14523213-RNA, Messenger,
pubmed-meshheading:14523213-Recurrence,
pubmed-meshheading:14523213-Sudden Infant Death
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pubmed:year |
2003
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pubmed:articleTitle |
Fetal hemoglobin synthesis determined by gamma-mRNA/gamma-mRNA + beta-mRNA quantitation in infants at risk for sudden infant death syndrome being monitored at home for apnea.
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pubmed:affiliation |
Division of Neonatology, Department of Pediatrics, University of Montreal, Ste-Justine Hospital and Research Center, Montreal, Quebec, Canada. harry.bard@umontreal.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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