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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2003-10-2
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pubmed:abstractText |
We have developed an automated system for the preparation of highly concentrated 188Re-perrhenate, diethylenetriamine pentaacetic acid (DTPA) and mercaptoacetyltriglycine (MAG3). The three procedural steps include concentration of 188Re-perrhanerate, chelation and purification and sterilization. The steps are operated by a small micro-controller. The eluted 188Re-perrhenate of 15 GBq/18 ml from 37 GBq 188W/188Re-generator was concentrated to 1.2 ml in 10 +/- 0.5 min with a recovery yield of 95 +/- 1.5%. We obtained the highest radiochemical yield of 95.4 +/- 2.8% and 98.5 +/- 1.2% for 188Re-DTPA and MAG3 at the oil bath temperatures of 95-97 degrees C and 93-97 degrees C, respectively.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0969-8043
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14522229-Brachytherapy,
pubmed-meshheading:14522229-Computer Systems,
pubmed-meshheading:14522229-Computing Methodologies,
pubmed-meshheading:14522229-Coronary Restenosis,
pubmed-meshheading:14522229-Equipment Design,
pubmed-meshheading:14522229-Equipment Failure Analysis,
pubmed-meshheading:14522229-Glycine,
pubmed-meshheading:14522229-Humans,
pubmed-meshheading:14522229-Isotope Labeling,
pubmed-meshheading:14522229-Pentetic Acid,
pubmed-meshheading:14522229-Radioisotopes,
pubmed-meshheading:14522229-Radiopharmaceuticals,
pubmed-meshheading:14522229-Rhenium,
pubmed-meshheading:14522229-Robotics,
pubmed-meshheading:14522229-Systems Integration,
pubmed-meshheading:14522229-Vascular Diseases
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pubmed:year |
2003
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|
pubmed:articleTitle |
Automated preparation of 188Re-labeled radiopharmaceuticals for endovascular radiation therapy.
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pubmed:affiliation |
Departments of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap-2dong, Songpa-gu, Seoul 138-736, South Korea. sjoh@www.amc.seoul.kr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies,
Validation Studies
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