Linked Life Data

14521326

Source:http://linkedlifedata.com/resource/pubmed/id/14521326

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-10-2
pubmed:abstractText
We set out to assess the performance and degree of agreement for the different automated hematology analyzers (AHAs) currently used within the Shanghai region. Analyzers from 5 different manufacturers were represented within the 114 hospitals that participated in this project: Abbott, ABX, Beckman Coulter, Nihon Kohden, and Sysmex. We determined the results obtained on 115 hematology analyzers in the 114 different hospitals for hemoglobin (HGB), red blood cell count (RBC), white blood cell count (WBC), hematocrit (HCT), and platelet count (PLT) from fresh anticoagulated blood samples from healthy donors. The maximum coefficients of variation (CV%) among instruments of the 3 main manufacturers (Abbott, Beckman Coulter, and Sysmex) for RBC, HGB, HCT, WBC, and PLT were 3.2%, 3.8%, 3.6%, 9.3%, and 10.8%, respectively. The maximum deviations observed among these parameters from the 5 major instrument groups were 0.74% (RBC), 2.24% (HGB), 6.37% (HCT), 6.97% (WBC), and 21.06% (PLT). Implementation of the regular, local external quality assessment program in the Shanghai region using fresh blood samples has resulted in a reduction of CV% values for the major clinically important CBC parameters (RBC, HGB, HCT, WBC, and PLT) within the instrument groups over time. An important result was that the CBC parameter CVs were also well within established US Clinical Laboratory Improvement Amendments of 1988 guidelines for AHA performance. Combined with a comprehensive education program, the Shanghai external fresh blood quality assessment program has resulted in closer agreement among the various AHA manufacturers, with only very small differences for RBC, HGB, HCT, WBC, and PLT counts. The success of this program has given us increased confidence in the comparability of results and subsequent patient management using the various types of AHAs currently in use in the hospitals within the Shanghai region.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1080-2924
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
175-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
External quality assessment of automated hematology analyzer performance using fresh human blood samples in Shanghai.
pubmed:affiliation
Shanghai Centre for Clinical Laboratory, Shanghai, Peoples Republic of China. shccl02@shccl.org
pubmed:publicationType
Journal Article, Comparative Study, Evaluation Studies