Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2003-10-1
pubmed:abstractText
Squalamine is an antitumor agent that has been shown to have antiangiogenic activity in animal models. This Phase I/IIA study was designed to assess the safety, clinical response, and pharmacokinetics of squalamine when administered as a 5-day continuous infusion in conjunction with standard chemotherapy every 3 weeks in patients with stage IIIB (pleural effusion) or stage IV non-small cell lung cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4108-15
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:14519633-Adult, pubmed-meshheading:14519633-Aged, pubmed-meshheading:14519633-Aged, 80 and over, pubmed-meshheading:14519633-Angiogenesis Inhibitors, pubmed-meshheading:14519633-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:14519633-Carboplatin, pubmed-meshheading:14519633-Carcinoma, Non-Small-Cell Lung, pubmed-meshheading:14519633-Cholestanols, pubmed-meshheading:14519633-Disease-Free Survival, pubmed-meshheading:14519633-Female, pubmed-meshheading:14519633-Humans, pubmed-meshheading:14519633-Infusions, Intravenous, pubmed-meshheading:14519633-Lactates, pubmed-meshheading:14519633-Lung Neoplasms, pubmed-meshheading:14519633-Male, pubmed-meshheading:14519633-Middle Aged, pubmed-meshheading:14519633-Neoplasm Staging, pubmed-meshheading:14519633-Paclitaxel, pubmed-meshheading:14519633-Patient Selection, pubmed-meshheading:14519633-Pleural Effusion, pubmed-meshheading:14519633-Survival Analysis, pubmed-meshheading:14519633-Time Factors
pubmed:year
2003
pubmed:articleTitle
A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer.
pubmed:affiliation
Department of Thoracic/Head and Neck Medical Oncology and Biostatistics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Clinical Trial, Phase II, Clinical Trial, Phase I