| pubmed-article:1451954 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1451954 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:1451954 | lifeskim:mentions | umls-concept:C0011849 | lld:lifeskim |
| pubmed-article:1451954 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:1451954 | lifeskim:mentions | umls-concept:C0678121 | lld:lifeskim |
| pubmed-article:1451954 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:1451954 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:1451954 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:1451954 | pubmed:dateCreated | 1993-1-6 | lld:pubmed |
| pubmed-article:1451954 | pubmed:abstractText | To examine determinants of basal metabolic rate we studied 66 Type 2 (non-insulin-dependent) diabetic and 24 healthy age- and weight-matched control subjects with indirect calorimetry and infusion of [3H-3-] glucose. Eight Type 2 diabetic patients were re-studied after a period of insulin therapy. Basal metabolic rate was higher in Type 2 diabetic patients than in control subjects (102.8 +/- 1.9 J.kg LBM-1.min-1 vs 90.7 +/- 2.8 J.kg LBM-1.min-1; p less than 0.01) and decreased significantly with insulin therapy (p less than 0.01). The basal rate of hepatic glucose production was higher in Type 2 diabetic patients than in control subjects (1044.0 +/- 29.9 vs 789.3 +/- 41.7 mumol/min; p less than 0.001) and decreased after insulin therapy (p less than 0.01). Hepatic glucose production correlated positively with basal metabolic rate both in Type 2 diabetic patients (r = 0.49; p less than 0.001) and in control subjects (r = 0.50; p less than 0.05). Lipid oxidation was increased in Type 2 diabetic patients compared with control subjects (1.68 +/- 0.05 vs 1.37 +/- 0.08 mumol.kg LBM-1.min-1; p less than 0.01) and decreased significantly after insulin therapy (p less than 0.05). The rate of lipid oxidation correlated positively with basal metabolic rate both in Type 2 diabetic patients (r = 0.36; p less than 0.01) and in control subjects (r = 0.51; p less than 0.01). These data demonstrate that basal metabolic rate, rates of hepatic glucose production and lipid oxidation are interrelated in Type 2 diabetic patients.(ABSTRACT TRUNCATED AT 250 WORDS) | lld:pubmed |
| pubmed-article:1451954 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1451954 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1451954 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1451954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1451954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1451954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1451954 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1451954 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:1451954 | pubmed:issn | 0012-186X | lld:pubmed |
| pubmed-article:1451954 | pubmed:author | pubmed-author:GroopLL | lld:pubmed |
| pubmed-article:1451954 | pubmed:author | pubmed-author:Franssila-Kal... | lld:pubmed |
| pubmed-article:1451954 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1451954 | pubmed:volume | 35 | lld:pubmed |
| pubmed-article:1451954 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1451954 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1451954 | pubmed:pagination | 962-6 | lld:pubmed |
| pubmed-article:1451954 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:1451954 | pubmed:meshHeading | pubmed-meshheading:1451954-... | lld:pubmed |
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| pubmed-article:1451954 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1451954 | pubmed:articleTitle | Factors associated with basal metabolic rate in patients with type 2 (non-insulin-dependent) diabetes mellitus. | lld:pubmed |
| pubmed-article:1451954 | pubmed:affiliation | Helsinki University Hospital, Fourth Department of Medicine, Finland. | lld:pubmed |
| pubmed-article:1451954 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1451954 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
