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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2003-9-30
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pubmed:abstractText |
Both cholecystokinin (CCK)-A and CCK-B receptors are expressed in the pancreas, and exogenous gastrin administration stimulates glucagon secretion from human islets. Although gastrin action has been linked to islet neogenesis, transdifferentiation, and beta-cell regeneration, an essential physiologic role(s) for gastrin in the pancreas has not been established.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:AbadirAmirA,
pubmed-author:BaggioLaurie LLL,
pubmed-author:BergerVeerleV,
pubmed-author:BousheyRobin PRP,
pubmed-author:DruckerDaniel JDJ,
pubmed-author:FinegoodDianeD,
pubmed-author:FlamezDaisyD,
pubmed-author:LiYazhouY,
pubmed-author:MarshallBess ABA,
pubmed-author:SchuitFransF,
pubmed-author:WangTimothy CTC
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pubmed:issnType |
Print
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1164-74
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:14517799-Animals,
pubmed-meshheading:14517799-Fasting,
pubmed-meshheading:14517799-Female,
pubmed-meshheading:14517799-Gastrins,
pubmed-meshheading:14517799-Glucagon,
pubmed-meshheading:14517799-Glucose,
pubmed-meshheading:14517799-Homeostasis,
pubmed-meshheading:14517799-Hypoglycemia,
pubmed-meshheading:14517799-Insulin,
pubmed-meshheading:14517799-Islets of Langerhans,
pubmed-meshheading:14517799-Male,
pubmed-meshheading:14517799-Mice,
pubmed-meshheading:14517799-Mice, Inbred C57BL,
pubmed-meshheading:14517799-Mice, Mutant Strains,
pubmed-meshheading:14517799-Receptor, Cholecystokinin B,
pubmed-meshheading:14517799-Receptors, Cholecystokinin
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pubmed:year |
2003
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pubmed:articleTitle |
Hypoglycemia, defective islet glucagon secretion, but normal islet mass in mice with a disruption of the gastrin gene.
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pubmed:affiliation |
Department of Medicine, Banting and Best Diabetes Centre, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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