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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2003-10-14
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pubmed:abstractText |
Elevated renin-angiotensin-aldosterone system activity correlates with left ventricular hypertrophy (LVH) and cardiovascular risk, but the relative contributions of angiotensin II and aldosterone remain unclear. This study compared LVH regression during treatment with the selective aldosterone blocker eplerenone, enalapril, and their combination in patients with hypertension.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
14
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pubmed:volume |
108
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1831-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14517164-Adult,
pubmed-meshheading:14517164-Aged,
pubmed-meshheading:14517164-Aldosterone Antagonists,
pubmed-meshheading:14517164-Amlodipine,
pubmed-meshheading:14517164-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:14517164-Antihypertensive Agents,
pubmed-meshheading:14517164-Double-Blind Method,
pubmed-meshheading:14517164-Drug Synergism,
pubmed-meshheading:14517164-Drug Therapy, Combination,
pubmed-meshheading:14517164-Enalapril,
pubmed-meshheading:14517164-Female,
pubmed-meshheading:14517164-Humans,
pubmed-meshheading:14517164-Hydrochlorothiazide,
pubmed-meshheading:14517164-Hypertension,
pubmed-meshheading:14517164-Hypertrophy, Left Ventricular,
pubmed-meshheading:14517164-Magnetic Resonance Imaging,
pubmed-meshheading:14517164-Male,
pubmed-meshheading:14517164-Middle Aged,
pubmed-meshheading:14517164-Myocardium,
pubmed-meshheading:14517164-Potassium,
pubmed-meshheading:14517164-Renin-Angiotensin System,
pubmed-meshheading:14517164-Spironolactone,
pubmed-meshheading:14517164-Treatment Outcome
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pubmed:year |
2003
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pubmed:articleTitle |
Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study.
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pubmed:affiliation |
University of Michigan Health System, Ann Arbor, Mich, USA. bpitt@umich.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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