Linked Life Data

14516874

Source:http://linkedlifedata.com/resource/pubmed/id/14516874

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2003-9-30
pubmed:abstractText
Information about the impact of race/ethnicity on adverse outcomes after percutaneous coronary intervention (PCI) in the modern era is limited. Using consecutive patients from the National Heart, Lung, and Blood Institute Dynamic Registry, this study investigated differences in clinical presentation, treatment strategy, and acute and long-term outcomes in 3,669 white, 446 black, 301 Hispanic, and 201 Asian patients who underwent PCI. All comparisons were made to whites. Blacks were more likely than whites to be younger, women, and to present with a higher prevalence of cardiovascular risk factors (hypertension, diabetes, and smoking). Hispanics tended to be younger, hypertensive, diabetic, and to be undergoing their first cardiovascular procedure. Asians were, on average, younger, men, and presented more often with hypertension and diabetes than whites. Although the rate of stent implantation was significantly lower in blacks compared with whites (63% vs 74%, p <0.001), angiographic and procedural success rates were high (> or =95%) and did not differ by race/ethnicity. In-hospital mortality (0.2% vs 1.7%, p <0.05) and death/myocardial infarction (MI)/coronary artery bypass grafting (CABG) (3.1% vs 5.5%, p <0.05) were lower in blacks. All other in-hospital complications were similar to whites. At 1 year, there were no statistical differences in cumulative adverse event rates by ethnicity; however by 2 years there was a modestly higher mortality rate (adjusted RR 1.87; 95% confidence interval 1.15 to 3.04) and adverse event rate (death/MI, death/MI/CABG) among black patients. Thus, although differences in patient demographics, clinical presentation, angiographic characteristics and treatment strategies did not impact the incidence of acute and 1-year adverse outcomes of non-whites, there appears to be a significant reduction in event-free survival among blacks by 2 years.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
773-8
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:14516874-African Continental Ancestry Group, pubmed-meshheading:14516874-Age Distribution, pubmed-meshheading:14516874-Angioplasty, Balloon, Coronary, pubmed-meshheading:14516874-Asian Continental Ancestry Group, pubmed-meshheading:14516874-Coronary Artery Disease, pubmed-meshheading:14516874-European Continental Ancestry Group, pubmed-meshheading:14516874-Female, pubmed-meshheading:14516874-Hospital Mortality, pubmed-meshheading:14516874-Humans, pubmed-meshheading:14516874-Incidence, pubmed-meshheading:14516874-Male, pubmed-meshheading:14516874-Middle Aged, pubmed-meshheading:14516874-Outcome and Process Assessment (Health Care), pubmed-meshheading:14516874-Platelet Glycoprotein GPIIb-IIIa Complex, pubmed-meshheading:14516874-Postoperative Complications, pubmed-meshheading:14516874-Sex Distribution, pubmed-meshheading:14516874-Survival Rate, pubmed-meshheading:14516874-United States
pubmed:year
2003
pubmed:articleTitle
Ethnic differences in the presentation, treatment strategy, and outcomes of percutaneous coronary intervention (a report from the National Heart, Lung, and Blood Institute Dynamic Registry).
pubmed:affiliation
New York University Medical Center, New York, New York 1016-649, USA. james.slater@med.nyu.edu
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.