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rdf:type |
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lifeskim:mentions |
umls-concept:C0023223,
umls-concept:C0034656,
umls-concept:C0055332,
umls-concept:C0067899,
umls-concept:C0087111,
umls-concept:C0205191,
umls-concept:C0282460,
umls-concept:C1522408,
umls-concept:C1697272,
umls-concept:C1704806,
umls-concept:C1707455
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pubmed:issue |
3
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|
pubmed:dateCreated |
2003-9-26
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|
pubmed:abstractText |
The well-known active chlorine compound chloramine T (CAT) with broad-spectrum antimicrobial activity is in common therapeutic use for leg ulcers with purulent coatings; however, this treatment is painful. The tolerability of the less aggressive N-chlorotaurine (NCT), an endogenous compound also produced in vivo by stimulated human granulocytes, could be superior.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0007-0963
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
149
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
590-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14510994-Administration, Topical,
pubmed-meshheading:14510994-Adult,
pubmed-meshheading:14510994-Aged,
pubmed-meshheading:14510994-Aged, 80 and over,
pubmed-meshheading:14510994-Anti-Infective Agents, Local,
pubmed-meshheading:14510994-Chloramines,
pubmed-meshheading:14510994-Chronic Disease,
pubmed-meshheading:14510994-Dermatologic Agents,
pubmed-meshheading:14510994-Double-Blind Method,
pubmed-meshheading:14510994-Drug Evaluation,
pubmed-meshheading:14510994-Female,
pubmed-meshheading:14510994-Humans,
pubmed-meshheading:14510994-Leg Ulcer,
pubmed-meshheading:14510994-Male,
pubmed-meshheading:14510994-Middle Aged,
pubmed-meshheading:14510994-Pain,
pubmed-meshheading:14510994-Taurine,
pubmed-meshheading:14510994-Tosyl Compounds,
pubmed-meshheading:14510994-Treatment Outcome,
pubmed-meshheading:14510994-Wound Healing
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pubmed:year |
2003
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pubmed:articleTitle |
Tolerability and efficacy of N-chlorotaurine in comparison with chloramine T for the treatment of chronic leg ulcers with a purulent coating: a randomized phase II study.
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pubmed:affiliation |
Institute of Hygiene and Social Medicine, Leopold-Franzens-University of Innsbruck, Fritz-Pregl-Str. 3, A-6010 Innsbruck, Austria. m.nagl@uibk.ac.at
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase II
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