Linked Life Data

14510877

Source:http://linkedlifedata.com/resource/pubmed/id/14510877

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-9-26
pubmed:abstractText
Although elderly patients are at an increased risk for skin infections, the chief culprits are no different than in younger patients. However, many of these organisms have developed resistance to antibiotics. Resistance increases the morbidity, mortality, and cost of treating infections. The mechanisms by which resistance occurs include efflux of antibiotic through a cellular pump, inactivation of the antibiotic by enzymes, or changes in the target affinity for the antibiotic. For dermatologic conditions in the elderly, documented resistance is seen in staphylococci, streptococci, and enterococci. Clinicians can reduce the development of resistance by following infection control and antibiotic use guidelines. To optimize the antibiotic effect and minimize adverse effects in the elderly, pharmacokinetic changes seen with aging should guide antibiotic choice and dosing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1396-0296
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
206-13
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Antibiotics and resistance in dermatology: focus on treating the elderly.
pubmed:affiliation
College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA. hutchisonlisac@uams.edu
pubmed:publicationType
Journal Article