Linked Life Data

14510476

Source:http://linkedlifedata.com/resource/pubmed/id/14510476

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-9-26
pubmed:abstractText
An effective and simple technology is required to identify genes that function in a particular phenotype of interest. A system for identification of genes with libraries of randomized ribozymes has a great potential to investigate gene functions and cellular pathways. This system has been used to identify genes that are relevant to several phenotypes. In vivo application of the library of ribozymes in mice model was also performed to identify genes involved in metastasis. Libraries of ribozymes might be used in vitro and in vivo to study various aspects of basic cell biology and disease processes including metastasis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:author
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-4
pubmed:dateRevised
2006-11-30
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Use of a ribozyme library for validation of gene functions and cellular pathways.
pubmed:affiliation
Gene Function Research Center, National Institute of Advanced Industrial Science and Technology, Central 4, 1-1-1 Higashi, Tsukuba Science City 305-8562, Japan.
pubmed:publicationType
Journal Article, Validation Studies