14507865

Source:http://linkedlifedata.com/resource/pubmed/id/14507865

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0022575, umls-concept:C0026809, umls-concept:C0314719
pubmed:issue	10
pubmed:dateCreated	2003-9-25
pubmed:abstractText	Neurturin has been identified as a neurotrophic factor for parasympathetic neurons. Neurturin-deficient (NRTN(-/-)) mice have defective parasympathetic innervation of their lacrimal glands. This study was conducted to evaluate tear function and ocular surface phenotype in NRTN(-/-) mice.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/DK52574, http://linkedlifedata.com/resource/pubmed/grant/EY11915, http://linkedlifedata.com/resource/pubmed/grant/R01-DK57038
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7703701
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Fluorescein, http://linkedlifedata.com/resource/pubmed/chemical/Histocompatibility Antigens Class II, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9, http://linkedlifedata.com/resource/pubmed/chemical/Mucins, http://linkedlifedata.com/resource/pubmed/chemical/Nerve Growth Factors, http://linkedlifedata.com/resource/pubmed/chemical/Neurturin, http://linkedlifedata.com/resource/pubmed/chemical/Nrtn protein, mouse
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	0146-0404
pubmed:author	pubmed-author:FarleyWilliamW, pubmed-author:HeuckerothRobert ORO, pubmed-author:LiDe-QuanDQ, pubmed-author:LuoLi HuiLH, pubmed-author:MilbrandtJeffreyJ, pubmed-author:PflugfelderStephen CSC, pubmed-author:SongXiu JunXJ
pubmed:issnType	Print
pubmed:volume	44
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4223-9
pubmed:dateRevised	2010-3-24
pubmed:meshHeading	pubmed-meshheading:14507865-Animals, pubmed-meshheading:14507865-Cell Count, pubmed-meshheading:14507865-Cornea, pubmed-meshheading:14507865-Disease Models, Animal, pubmed-meshheading:14507865-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:14507865-Fluorescein, pubmed-meshheading:14507865-Fluorescent Antibody Technique, Indirect, pubmed-meshheading:14507865-Fluorophotometry, pubmed-meshheading:14507865-Goblet Cells, pubmed-meshheading:14507865-Histocompatibility Antigens Class II, pubmed-meshheading:14507865-Interleukin-1, pubmed-meshheading:14507865-Keratoconjunctivitis, pubmed-meshheading:14507865-Lacrimal Apparatus, pubmed-meshheading:14507865-Matrix Metalloproteinase 9, pubmed-meshheading:14507865-Mice, pubmed-meshheading:14507865-Mice, Knockout, pubmed-meshheading:14507865-Mucins, pubmed-meshheading:14507865-Nerve Growth Factors, pubmed-meshheading:14507865-Neurturin, pubmed-meshheading:14507865-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:14507865-Tears
pubmed:year	2003
pubmed:articleTitle	Neurturin-deficient mice develop dry eye and keratoconjunctivitis sicca.
pubmed:affiliation	Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX 77030, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't